AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREWalnut’s Malik Khouzam voted Southern California Boys Athlete of the Week A spokesman for the Coalition for the Advancement of Medical Research, which advocates federal funding of stem cell research, cautioned that despite the goal of avoiding ethical quandaries, the new approaches “will not sit well with many who oppose embryonic stem cell research.” In the standard method of harvesting stem cells, researchers wait five days or so after fertilization until the embryo has become a ball of up to 150 cells. They obtain stem cells from the interior of the ball, which destroys the embryo. One of the new mouse studies makes use of a lab technique from fertility clinics, called pre-implantation genetic diagnosis or PGD. It is used to screen embryos for genetic disorders. In the study, researchers plucked a single cell from eight-cell mouse embryos, which were about two days old. While fertility clinics use such cells for genetic testing, the researchers cultured the plucked cells and found they behaved like embryonic stem cells. The embryos, meanwhile, went on to produce mice. The result suggests that a clinic could let the cell removed for PGD divide into two, then use one resulting cell for genetic testing and the other to establish a stem cell line, said Robert Lanza of Advanced Cell Technology in Worcester, Mass., an author of the study. NEW YORK – Two new mouse experiments may show how to obtain human embryonic stem cells without ethical hurdles, a step that could allow federal funding for such research, scientists reported Sunday. Currently, scientists must sacrifice human embryos to harvest such cells, which can form any tissue type and are seen as valuable for studying and treating illnesses like diabetes and Parkinson’s disease. Objections to the embryo destruction have led to a ban on federal funding for such work, which scientists say hampers research. With new methods, detailed Sunday in the online edition of the journal Nature, scientists seek to obtain the cells without destroying embryos. An official with the U.S. Conference of Catholic Bishops said the two reported techniques still raise ethical objections, although a spokesman for a group of Roman Catholic bioethicists called one of the methods a step in the right direction. But Richard Doerflinger, a deputy director for the Catholic bishops conference, said PGD itself is unethical. It poses a risk of harm and is mostly an effort “to select out genetically imperfect embryos,” he said. The second mouse study used a modified form of therapeutic cloning – a technique that aims to generate stem cells that genetically match a patient – for either treatment or research. Results were reported by Dr. Rudolf Jaenisch and Alexander Meissner of the Whitehead Institute for Biomedical Research and the Massachusetts Institute of Technology in Cambridge, Mass. As with normal therapeutic cloning, Jaenisch and Meissner took eggs whose DNA-containing nuclei had been removed and inserted in each one a nucleus from a body cell of a mouse. But before the insertion, they blocked the action of a key gene in the nuclei, to ensure the eggs could not produce an embryo that can be implanted in a uterus. Yet, the eggs divided and grew enough to yield stem cells. This modified technique, called altered nuclear transfer, has been championed by Dr. William Hurlbut of Stanford University, a member of the President’s Council on Bioethics. He said the abstract cluster of cells the egg produces is not an embryo but a “nonembryonic entity” that lacks an embryo’s developmental potential. “You don’t create a living being,” he said. Doerflinger disagreed, saying the technique appears to create and then destroy an embryo, which would make it unethical. But the Rev. Tad Pacholczyk, director of education for the National Catholic Bioethics Center in Philadelphia, called the approach a step in the right direction. Scientists are already discussing a modified version in which adding the nucleus to the egg would result in a single stem cell, not an embryo, he said. Seen in that light,the mouse study “is very encouraging,” he said. “It reminds us that we have certain tools at our disposal in the scientific armamentarium that can be used in the direction of seeking an answer to the ethical impasse.” 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set!
ANAHEIM — It’s been a trying season for A’s reliever Yusmeiro Petit, both on and off the field.At 92 innings pitched on the year, Petit has already surpassed his total from 2017 with the Angels as he finishes the season set to lead the majors in innings pitched by a relief pitcher for the second consecutive season. The 73 games he’s appeared in are by far the most in his 11 big league seasons.It’s a tough grind on his arm, which at 33 years old still finds a way to get batters out on a …
“Giant prehistoric penguins? In Peru?” puzzled a reporter on Science Daily. “It sounds more like something out of Hollywood than science,” but a fossil penguin you could look eye to eye with has been found that far north. “We tend to think of penguins as being cold-adapted species,” said one of the discoverers,” but not all species live in cold waters. These fossils “seem to contradict some of what we think we know about the relationship between penguins and climate,” she said. This one was surprising not only for its locale and size (1.5m standing height). It comes from a stratum considered “tens of millions of years earlier than expected and during a period when the earth was much warmer than it is now.” See also National Geographic and EurekAlert.Summing up: (1) the fossils are tens of millions of years out of order. (2) One of the two species was larger than any penguin alive today – as tall as a human. (3) It had a larger beak: “Both new species had long narrow pointed beaks — now believed to be an ancestral beak shape for all penguins.” (3) It was found at an equatorial latitude, indicating a richer biodiversity in the past. (4) Everyone was surprised by these findings. Conclusion: another victory for evolutionism. Encore: (5)… “during a period when the earth was much warmer than it is now” (36 million years ago). Conclusion: we must take drastic measures because humans are responsible for global warming.(Visited 8 times, 1 visits today)FacebookTwitterPinterestSave分享0
7 October 2014It’s all systems go for the 35th annual Crime Stoppers International (CSI) Conference, which is to be hosted by Crime Line and the South African Police Service (SAPS), in Cape Town, next week. This is the first time the conference will be hosted in Africa.Crime Stoppers is an international body that is active in over 26 countries around the world through programmes that are driven by anonymous tip-offs passed on to law enforcement.The four-day conference, which will be held from 12 to 15 October, will attract hundreds of local and foreign delegates, offering them a comprehensive look at crime globally, but with actions and solutions that they can take home.The conference will be held under the theme: It’s Time.Issues to be discussed at the conference include crimes against economies; environmental crimes; corruption; associated crimes; and skills development. South African national police minister Nkosinathi Nhleko and national police commissioner General Riah Phiyega officially opened the conference on Monday 6 October together with CSI president Alex MacDonald. Other South African delegates at the conference included environmental affairs minister Edna Molewa, sport and recreation minister Fikile Mbalula, deputy police minister Magdalene Sotyu, the Public Protector Advocate Thuli Madonsela, head of the Special Investigation Unit, Vas Soni, and the recently appointed commissioner for the South African Revenue Service, Tom Moyane.Speakers at the event include US Secret Service officer Michael Burgin talking about cybercrime, while Stanley Jacobs from the London Community Rehabilitation Company (UK Probation Service) will talk about Integrated Offender Management.Phiyega said it was important to bring the various partners in the fight against crime together and to strengthen the partnerships at all levels.“We also want to use the conference to network and to share our experiences and expertise. We all need to work together to fight crime.’Head of South Africa’s Crime Line and chairman of the conference organising committee, Yusuf Abramjee, said registrations are still open and he appealed to “anyone who wanted to create a safer South Africa and a safer world to join the global movement and register for the conference’.He added that it was necessary for “everyone to join hands and to take the fight against crime to the next level’.A special scholarship programme has also been established to support some 100 crime fighters from law enforcement, community policing forums and civil society to attend the conference.For conference and registration details, visit www.crimestoppers-conference2014.com. – SAnews.gov.za
The adventure of geocaching goes four-wheeling. Geocachers with four-wheel drive vehicles seem resolved not to let little things like mountains and deserts and large expanses of razor-sharp shrubs deter them from finding caches.Off-roading and geocachingThe roots of 4×4 geocaching run deep into the decade long history of geocaching. Thousands of geocaches with “off-road” attributes now span the globe from Albania to Zambia and almost everywhere in between.Watch geocachers from Team Red Rubicon explore the wilds of Colorado, USA in search of geocaches.Explore all the Lost & Found videos, including a geocache in space, here.Share with your Friends:More SharePrint Related”Desert Geocaching” A Geocaching.com Lost & Found VideoNovember 16, 2010In “Community””Night Caching” A Geocaching.com Lost & Found VideoNovember 23, 2010In “Community””Newbie Geocaching 101” A Geocaching.com Lost & Found VideoDecember 7, 2010In “Lost & Found Stories”
frederic lardinois A Comprehensive Guide to a Content Audit Related Posts Guide to Performing Bulk Email Verification Tags:#Trends#twitter#web Facebook is Becoming Less Personal and More Pro… In its current state, Twitter is a strange mix of real-time features like search and the slow polling mechanism that desktop clients use to grab new messages. As Twitter puts a limit on how many times per hour a client can check for updates, most of the conversations on Twitter are slow and arduous. When Seesmic released its new desktop and web applications last week, however, the company also mentioned that its applications would soon be able to update Twitter streams in real time, including @replies and direct messages. While the Seesmic team was tight-lipped about how exactly they are going to do this (maybe by tapping into Twitter’s Streaming API?), we can’t help but wonder how this will change the dynamics on the service.Twitter as a Chat RoomCurrently, conversations on Twitter are asynchronous and sluggish. If they happened in real-time, however, Twitter would start to look and feel more like an IM client. Even on FriendFeed, which was once seen as a possible Twitter challenger but which never quite got any mainstream traction, conversations now happen in real time. While Twitter is often mentioned as a vehicle for real-time conversations, in reality, conversations on Twitter aren’t happening in real time at all.Once Twitter turns into more of a chatroom, both Twitter’s website and third-party clients will also have to improve the way they display these conversations. Seesmic’s ‘message’ view looks like a step in the right direction. The Seesmic web app features a TweetDeck-like column-based view of your Twitter streams and searches, but it also separates ‘real’ conversations that you participate in from the rest of the application. Other desktop apps like Nambu for the Mac feature rudimentary support for displaying conversation threads, but most clients currently don’t do a very good job at highlighting conversations and mostly look at Twitter as a broadcast medium.Once our streams really start moving on Twitter, we will also need better ways to filter and manage our subscriptions (including better spam filters). Right now, scanning a list of updates is easy, and most clients support search and the ability to create groups, but maybe automatic filtering based on the kind of messages we pay attention to will also help us to manage the information stream. What Do You Think?We will have to see how all of this will play out in the next few months once Seesmic (and others, we assume) will release their updated clients, but we think that this could potentially take Twitter into a completely new direction. The Dos and Don’ts of Brand Awareness Videos
Black Friday crazy is upon us, that one day of the year where Americans take leave of their senses and go out and buy all their holiday gifts 32 days early, and yet still manage to panic-shop on Christmas Eve. If you insist on participating in this shoppingpalooza, these iPhone and Android apps can help you find the best price for the items you seek.Get The BasicsIf you use nothing else, get yourself a basic barcode scanner app. A lot of stores display QR codes for items and even if you plan to buy in-store and not online later, scanning these codes can get you more information about the item that might not be in the display. The app I like is ShopSavvy, which takes care of these basic features and also conducts local and online searches to see if it’s available anywhere else cheaper. The other thing I like about this app is that it can store credit card and shipping information and if you’re in a supported store, like WalMart or Barnes & Noble, you can buy the item with just one swipe. I love following my kids around in stores with this functionality, because I can surreptitiously buy the item right then and there without having to come back to the store or have them see me buying it. (Free. Available for iOS, Android.)Dare To CompareIf I’m going to commit to a shopping app, I would like it to have not just price comparisons, but also product reviews. If I am checking out a really snazzy-looking item in the store, I really don’t want to get home and find out that it’s had some reported issues like, oh, catching fire. I use Google Shopper as a steady guide to search for product reviews and conduct pricing checks. It’s accurate, delivers robust results and the integration with Google Maps makes it a great tool for finding nearby stores if you’re in a new locale. This app just got an update in November and now features a Sales section listing local weekly discounts in your area, so you can point the car in the right direction in the first place. (Free. Available for iOS, Android.)You can’t talk holiday shopping these days without bringing up Amazon (a sentence I’m sure just thrilled its PR team, but it’s true nonetheless). The fact is, as largest retailer on the Internet, low prices and low- to no-cost shipping on orders, it would be silly to ignore Amazon as a source for your holiday (or any other shopping needs), especially if money is tight. Amazon has two apps to use for your mobile device, and it’s important to know the difference. The Amazon Mobile app is a mobile gateway to the company’s commerce site. The even more useful Price Check for Amazon does pretty much what you would expect: like Google Shopper and other product/price comparison apps, it scans an item and let’s you know what that item is going for elsewhere – except with the Price Check app, “elsewhere” means Amazon, period. (Free. Available for iOS, Android.)It is certainly true that using apps like Google Shopper and Price Check for Amazon could result in you performing what retailers derisively refer to as “showrooming,” where shoppers come into the store, scan an item, and promptly leave to purchase it elsewhere or online. This practice is kicking retailers’ collective butts, since their business models rarely enable them to compete with the pricing models of online outlets, just as small businesses struggle to compete with the big-box stores. This is something about which you will have to make a personal choice as you shop with these apps, weighing potential savings against local service and supporting your community.Something For Every DayFinally, Key Ring Reward Cards is my new favorite shopping app. By scanning your loyalty cards for various stores that you have in your wallet or on your key ring, you can virtually store them on your phone and free up your wallet from these cards. To make sure they work, you can take photos of the front and back of your card, which is also useful for any loyalty programs that might be directly supported by the app. Most stores handle these well, though a grocery store’s laser scanner might choke trying to read the screen-displayed barcode. If the loyalty program is supported, you can also get weekly circular sales information and notices of special discounts. Just be warned, if you have privacy issues with store loyalty programs, Key Ring Reward Cards isn’t going to help (Free. Available for iOS, Android.)Best Black Friday AppsAll of the apps listed above have the benefit of being usable year-round. But what about apps for this coming weekend? Lots of stores have their own dedicated Blak Friday apps, but those are mostly a waste of time. Instead, look for the apps that pull in the best deals from multiple places. One of the most popular apps in this category is DealNews’ Black Friday app, which aggregates news and ads of deals that may be happening in stores near you. You can even check out “leaked” ads that retailers let slip to the public with a wink. Since the app is geo-specific, you can target store near wherever you are. (Free. Available for iOS, Android.)Another app for Black Friday is TGI Black Friday, which offers similar aggregation of ads for nearby stores. It’s very similar to DealNews’ app, but TGI Black Friday fans swear by it. (Free. Available for iOS, Android.)No matter how you like to shop on Black Friday – or even if you wait till Christmas Eve – these apps should help ease the pinch on your pocketbook and ensure a smoother shopping process.Image courtesy of Shutterstock. Why Tech Companies Need Simpler Terms of Servic… A Web Developer’s New Best Friend is the AI Wai… Top Reasons to Go With Managed WordPress Hosting 8 Best WordPress Hosting Solutions on the Market Tags:#e-commerce brian proffitt Related Posts
PANAJI: The front trolley of the Ernakulam–Lokmanya Tilak Terminus Duronto Express derailed between Sawantwadi Road and Zarap stations in Ratnagiri around 3 p.m. on Thursday. No casualties or injuries were reported.An accident relief medical van and accident relief trains were sent t from Ratnagiri and Verna respectively. Konkan Railway officials left for the site too. Train traffic was affected, but restored at 7.20 p.m., an official said. Passengers can visit www.konkanrailway.com or call 022–27587939 for train inquiry.